All-natural. Safe to swallow. Fluoride-free. Makes toothbrushing fun! Spry offers the proven benefits of xylitol. It cleans gums and teeth and promotes a positive oral environment for the healthy development of emerging teeth when used asp art of a complete oral hygiene program. Can be used with a Spry Pacifier or beginner toothbrush. For more information go to www.xlear.com. Made in USA.